You don't need a highway sign to know when you've crossed from California into Nevada: the flashing lights and elaborate marquees of casinos announce legal gambling in garish hues. But you'll find more here than tables and slot machines. Reno, the Biggest Little City in the World, has a vibrant arts scene and a serene downtown RiverWalk. And when you really need to get away from the chip-toting crowds, you can hike through pristine wilderness at Lake Tahoe–Nevada State Park, or hit the slopes near Incline Village.

For more information on Lake Tahoe, please see our additional coverage in California.